Journal CME

In alignment with our educational mission, the Clinical Immunology Society from time to time provides CME-accredited activities via our website. These activities aim to expand the outreach of our educational offerings, and fulfill our desire to address the needs of our target audience.


Method of Participation

In order to receive CME credit:

  • Select and read the Journal CME article from Journal of Clinical Immunology, along with its learning objectives and faculty disclosure information
  • Provide CIS with your contact information by logging in or by registering
  • Complete the post-test and evaluation questions
  • After you receive a passing score on the post-test you will be given the option to print a certificate.

Available Articles

New CME Articles


"Genetic Mosaicism as a Cause of Inborn Errors of Immunity"
Aluri, J., Cooper, M.A.
J Clin Immunol (2021).
"STING-Mediated Lung Inflammation and Beyond"
Frémond, ML., Crow, Y.J. 
J Clin Immunol 41, 501–514 (2021).

Previous CME Articles

"Human IκBα Gain of Function: a Severe and Syndromic Immunodeficiency"
Boisson, B., Puel, A., Picard, C. et al.
J Clin Immunol. July 2017, Volume 37, Issue 5, pp 397-412

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"Adenosine Deaminase (ADA)-Deficient Severe Combined Immune Deficiency (SCID): Molecular Pathogenesis and Clinical Manifestations"
Kathryn L. Bradford, Federico A. Moretti, Denise A. Carbonaro-Sarracino, Hubert B. Gaspar, Donald B. Kohn
J Clin Immunol. October 2017, Volume 37, Issue 7, pp 626-637

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"FOXN1 Deficiency: from the Discovery to Novel Therapeutic Approaches"
Gallo, V., Cirillo, E., Giardino, G. et al.
J Clin Immunol. November 2017, Volume 37, Issue 8, pp 751-758

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"Clinical Manifestations and Pathophysiological Mechanisms of the Wiskott-Aldrich Syndrome"
Candotti, F.
J Clin Immunol. January 2018, Volume 38, Issue 1, pp 13-27

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"Deficiency of Adenosine Deaminase 2 (DADA2): Updates on the Phenotype, Genetics, Pathogenesis, and Treatment"
Meyts, I. & Aksentijevich, I. J Clin Immunol (2018) 38: 569.

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"RAG Deficiency: Two Genes, Many Diseases"

Delmonte, O.M., Schuetz, C. & Notarangelo, L.D. J Clin Immunol (2018).


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"Life-Threatening Infections Due to Live-Attenuated Vaccines: Early Manifestations of Inborn Errors of Immunity"

Pöyhönen, L., Bustamante, J., Casanova, JL. et al. J Clin Immunol (2019) 39: 376.


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"WHIM Syndrome: from Pathogenesis Towards Personalized Medicine and Cure"

Heusinkveld LE, Majumdar S, Gao JL, McDermott DH, Murphy PM.  J Clin Immunol (2019) Aug; 39(6):532-556.


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"Immune Dysregulation and Disease Pathogenesis due to Activating Mutations in PIK3CD—the Goldilocks’ Effect"
Stuart G. Tangye, Julia Bier, Anthony Lau, Tina Nguyen, Gulbu Uzel, Elissa K. Deenick
J Clin Immunol (2019) 39: 148


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"Human STAT1 Gain-of-Function Heterozygous Mutations: Chronic Mucocutaneous Candidiasis and Type I Interferonopathy"
Okada, S., Asano, T., Moriya, K. et al.
J Clin Immunol 40, 1065–1081 (2020).

"Lazy Leukocyte Syndrome—an Enigma Finally Solved?"
Etzioni, A., Ochs, H.D.
J Clin Immunol 40, 9–12 (2020).

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Accreditation Statement

The Clinical Immunology Society is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation Statement

The Clinical Immunology Society designates this educational activity for a maximum of 1.00 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Commercial Supporter Information

There is no commercial support for Internet Journal CME.

Hardware/Software Requirements

Adobe Acrobat Reader™ is required to view the Journal Articles.


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Provider Contact Information

If you have any questions Online Journal CME, please contact the CIS Office.


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Policy on Privacy and Confidentiality

CIS will collect and store information you provide in this Internet educational activity for the purposes of enabling us to register your participation in the activity, to assist with administrative and planning purposes, for future planning and development of educational offerings and to allow the compilation and analysis of statistics relevant to CIS.

The information that you provide in this Internet educational activity including without limitation any feedback obtained during the activity, will be used by CIS to offer, provide and continue to improve CIS educational offerings and other services.

CIS will not otherwise, without your consent, use or disclose your personal information for any purpose unless it would reasonably be expected that such a purpose is related to the offer, provision and improvement of CIS or where such purpose is permitted or required by law.



The CIS will document that it owns the copyright for, or has received permissions for use of, or is otherwise permitted to use copyrighted materials within a CME activity on the Internet.